i believe rsd can indirectly cause death. my heart and immune system have weakened since i've had rsd and i feel like my body is slowly deteriorating. i don't know of anyone dying from rsd but do know of somone who committed suicide. don't know if that was the reason but they did have rsd and depression. don't mean to sound depressing. just telling you what i know to be true. having had rsd for almost four years, has made me sicker then i've ever been in my life. hope they find a cure soon or a way to go into remission for us all.