It may be the result of overdosage ...remember sinemet is chemical and human body has a maximum capacity to safely house this drugs , though different people has different capacities. Mine is about4-5 sinemet a day and beyond thus thresholds dystonia will be very serious ....
Quote:
Originally Posted by dwyerk60
Hello,
I am writing as a daughter of a mother (age 76) with PD (12+ years). She has somehow ended up taking 16+ Sinemet a day (2 tablets 25/100mg every 2 hours upon waking). This seems extremely high and well beyond the what is recommended. She 'lives' on pills and her quality of life is diminishing every day.
She also takes 20mg a day of Celexa to deal with the depression. She used to be so active and social and is now isolated in her apt. Several times a day she also has 'spells' or 'episodes' where suddenly her jaw will get stiff, her hand will cramp up, her walking is impaired, her breathing increases and she has to lie down (this year she started taking 1mg of Ativan three times a day to try and combat these spells). Once the spell is over she can resume a routine.
WE are at a loss but now wonder if the spells may be related to the high dose of Sinemet she takes?
Any thoughts? Comments? Getting desperate to help my Mom!
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