I've been on the interferon's, copaxone, tecfidera, I'm done. I can't take the shots due to allergic reactions to the meds. Same with the oral meds. I'm JC+ so i can't take tysabri and too scared to try gilenya. I'm DMD free and I only symptom management and feel better for it. I do wish you luck on rebif. If anything, I'm no longer afraid of needles