i had alot of digestion problems and gerd and so forth. I had it really bad for many years. It turned out to be a medication I was on and never in a million years would I have thought. I naturally assumed it was 100% PN related. It was a Beta blocker. Once I was switched to a different one it resolved within 2 days. In saying that, PN does cause stomach issues and I probably am affected to some degree, since my PN is extensive but the worst most intolerable gut issues was indeed med related. Have you looked at that possibility? Aussie