I noticed improvement (slight) after that 2nd night, as I could swallow pills again.. for the first time in months, however I still felt pretty weak.. three weeks later when I had my first loading dose... i woke up that 4th day afterwards, grabbed my phone and immediately could tell my hands hand strength.. it was an absolute miracle.. it fixed me back to about 99%.. it was amazing!!!! Since I hadn't been able to smile for so long, I think I smiled until that IVIG wore off! Good luck, I hope you feel better soon!