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Old 01-19-2015, 03:30 PM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

I had a drug induced lupus from lisinopril. I took it for years until I had a crisis and had to have it changed.

ACE inhibitors are derived from snake venom and create an excess of bradykinin (a biogenic amine) which dilates blood vessels. But it causes all sorts of grief for some people who cannot clear it away fast enough to be normal otherwise.
The enzyme to clear it away is called C-1 inhibitor, and some people are low in this genetically.

I'd discuss changing your medication with your doctor. It might be a huge surprise for you to see the symptoms fall away like mine did. Lisinopril was causing me mega grief, and since stopping it I control my BP with a small dose of beta blocker which is much less than before.

Do a search on bradykinin... you'll see.
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