Quote:
Originally Posted by Plantagenet
"If you have this mutation, you cannot have Imuran"
I hesitate to interject on another's thread but am puzzled as to the reason for this I am not questioning it but am just ignorant of the factors behind it. And seeking enlightenment.
Regards John
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Poor metabolizers of CYP2D6:
http://en.wikipedia.org/wiki/CYP2D6
Normal doses of drugs will build up if you are a poor metabolizer with this mutation. They can then become toxic. Sometimes a reduced dose could be figured out, but sometimes a drug is too toxic to mess with. Finding complete lists on the net is difficult...but if you look a drug up in detail, the pharmacology part will give metabolic information.
www.rxlist.com for example does provide this.
This is the pharmacology of Imuran:
http://www.rxlist.com/imuran-drug/cl...armacology.htm
Major drug interactions:
http://www.rxlist.com/imuran-drug/si...actions.htm#DI
Drugs.com has a good drug checker that will go into detail about this drug when used with others.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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