Thanks Annie.. It's been happening all these years, but used to seem milder.. they aren't sure.. (of course- i'm still a mystery), But I think that just has to be a clue with all of this.. My tongue when this happens (only with exertion of it), feels just like the rest of my muscles with exertion.. I have wondered if a vasculitis would show up like that? all of my esr/sed rates are always negative.. but I know that doesn't necessarily mean anything. It's like my muscles aren't utilizing the oxygen .. are there conditions that do that generalized that your aware of?