The protocol in Australia, is that a titre level of 1.5 is the cut-off amount for safe use of the drug (I am 2.406 - grrr.....but I have still been taking it - naughty).

Good luck with it all -- the incidence of PML is still very low for the first two years - get all the benefits you can I say!

It's all about what risk level you can live with - just make sure you know all the risks so you can make the most informed decision.