Mrs. D, that was me. I was on Cipro for six months (that's right, six months) but it was several years ago. I did not experience any neurological symptoms at that time though so I don't know what part, if any, it had in where I am today (I was dx'd with IPN August 2012).

I have discussed the Cipro history with my current doctor and as with most potential causes, his response is that we will never know so we should not spend too much time thinking about them as it would not change our course of action (treating symptoms). He tries to understand and be supportive which I think can be difficult for someone who has not experienced NP.

As my PN progresses, it becomes increasingly more challenging to enjoy my life so I do spend a lot of time researching, looking for potential causes, trying to figure out how I can halt the progression. What is intriguing about MTHFR is that I have those two bad mutations of a gene that many studies point to neurodegenerative diseases among other things. Sounds like a potential cause of IPN to me.

I think my doctor views me as experimental and he would be right. But I have to be this way. Too little is known about PN, and not enough is being done. I can't give up.