Quote:
Originally Posted by mrsD
Since your testing is not revealing much ....I'd consider that your past RA treatments may have caused your neuropathy.
Plaquenil and other DMARDs like methotrexate, can damage the DNA of cells. Plaquenil is related to the fluoroquinolone antibiotics and as a quinolone has potential to cause nerve damage.
http://www.ncbi.nlm.nih.gov/pubmed/11128688
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This is an interesting point thanks Mrs D. The neurophysiologist doctor made the same point. Only thing which possibly conflicts is that the strange surges of heat in my wrists and burnjng soles started before my RA began. However these might just have been hormonal signs as my menopause was just underway then. The pins and needles started when I had been on Methotrexate for 6 months and hydroxichloraquine for 3 months. But wouldn't these be improving now I've been off them for 8 months at least rather than worsening/ becoming more intense and widespread? Mat