Have you guys who wake up at 5 am or so tried eating a snack of complex carbs or protein before bed ? Your brains may be needing energy. The energy from food only lasts 7 to 8 hours, even less for some. Then, the liver needs to release ketones to feed the brain. If the ketones are not enough, the brain becomes energy deficient and may wake up. This is even more problematic if your body is not good at using fat for energy.