I am on amitriptyline to help with sleeping. I am almost unable to sleep without taking it. I have been on it for a year at a low dose of 100 mg. I found that most of the fatigue went away after 2-3 months.

It takes about an hour for me to feel sleepy. I also need to fall into a deep sleep, it stopped the running dream feeling I had. I went weeks feeling like I never slept until the doctor gave me amitriptyline.

I take 100 mg of Topamax for the headaches (again a low dose).

This are both clear cut for me. I don't sleep without the amitriptyline and I have daily headaches with the Topmax.