Hi Starznight,

The only thing for the treatment of an exacerbation (relapse, attack, flare-up) are steroids.

On a positive note; exacerbations can resolve on their own. Steroids might help the exacerbation resolve quicker...but not always.

I have had 5 exacerbations and only used steroids twice.

I am guessing Acthar Gel is in the same category of the other medications you mentioned but it is used for exacerbations, although it is pricey.
http://www.nationalmssociety.org/Tre...P-Acthar%C2%AE