Quote:
Originally Posted by zanpar321
This is very interesting as it once again shows that some folks for some reason are just unable to absorb B1 (and likely other B vitamins) and it causes big problems like that detailed in this paper and may also be at the root of PD, MS, chronic fatigue etc. I wonder if Benfotiamine (a fat based thiamine) and doesn't apparently get processed by the gut but goes to the liver instead, may be nearly as good as intravenous thiamine uptake.
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I've wondered for years if the Choroid Plexus may be at the heart of the problem regarding folks that have trouble absorbing B vitamins. Apparently, the Choroid Plexus acts as a filter to protect the brain from mercury etc. so if its damaged by too much mercury maybe the brain can't transport enough B1 to stay healthy.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126155/
" These results were interpreted as showing that the entry of total thiamine into the brain and CSF from blood is regulated by a saturable transport system, and that the locus of this system may be, in part, in the choroid plexus."
http://www.ncbi.nlm.nih.gov/pubmed/1267006