My wife was diagnosed with Parkinson's 14 years ago and had deep brain stimulation 6 years ago which has been a blessing, yet her use of 25/100 sinemet has increased to 10 times a day with wearing off problems and having to wake up twice in the night to take the meds which contributed to daytime fatigue. A week and a half ago she switched to Rytary 36.25/145 taking 3 pills three times a day
7am, 3pm, 11pm according to the prescribing recommendations provided by Impax. She had occasional dizziness the first 2 days but this resolved with time and she has none of the side effects that are listed as possibilities. The results she has had so far are excellent-better energy and speech, much better mobility
with significantly less off time and whole nights of uninterrupted sleep which has reduced the fatigue factor to a point where a short afternoon nap lets her bounce back. Parkinson's is still with her but Rytary has mitigated many of the issues she was facing under the old medication regime. So far so good. We worked carefully with our family physician who was totally supportive of trying Rytary.