I'd fire MG and be done with it.
Mestinon is a real problem at night for a lot of people. Bladder muscles get weaker when it wears off, and that's usually what wakes me up.
Waking up a few times at night does suck, but what's the alternative? Timespan is useful for some people, I suppose, but for others it's not enough of a dose and can be erratic.
Here's a direction: You need an overnight oximetry, at the least. A sleep study would be better.
Good grief. This lackadaisical care is getting to be a habit of physicians. Sorry, JJ.
Annie