I've only had the getting lost happen once. And I am just hoping it was because I was seriously distracted.

Nope, I'm not taking any medication regularly, other than Neurotin/Gabapentin (just started it last month) for the burning pain I feel in my arms/hands. (I had to call and see my regular neuro because the burning wouldn't stop. I waited for a week and then it took another week for the neurotin to start working.)
None of the migraine meds they've ever put me on have worked.