Thread: Levodopa Dose Equivalency
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Old 03-25-2015, 04:48 PM
johnt johnt is offline
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Location: Stafford, UK
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johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
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The FDA have released a file "Full Prescribing Information" for Rytary:

http://www.accessdata.fda.gov/drugsa...312s000lbl.pdf

Table 1 of the file shows the dose of Rytary for people converting from immediate release carbidopa-levodopa.

Total daily dose (mg)
Levodopa,Rytary
400-549,855
550-749,1140
750-949,1305
950-1249 ,1755
>=1250,2340 or 2205

The relationship between Rytary and levodopa is non-linear. Anyone know why?
But, roughly speaking:
100mg levodopa = 170mg Rytary

John
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