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Old 04-01-2015, 05:04 PM
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mrsD mrsD is offline
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

High folate in the presence of low B12 is called the folate trap.

It is kind of complex...

The MCV in the CBC will be elevated or very very high and almost out of range when B12 is low.

People with neuro signs severe enough for a wheelchair or lost vision, may not recover 100% when B12 is fixed and returns to a more normal level. This damage would be at the spinal cord level, and be demyelinating.

But most people do get better, but it may be slow going.

http://www.ncbi.nlm.nih.gov/pubmed/6115113
If you type methyl folate trap into Google and look at images there are many graphs that may help understand.

You can see why doctors don't really understand all this. It is really difficult, and I only have a minor understanding of it too.

The testing to run would be the methylation DNA testing for MTHFR.

More at MTHFR.net
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