Ellsac's descriptions is pretty accurate. The worst of the procedure is the numbing shot, so it's not bad at all. You leave with a band-aid and instructions to keep dry for a few days.

I had 3 sites done on each leg. Mine were the typical locations...ankle, just above knee and thigh. Some doctors only do two sites. You need at least two site in order to determine length/non-length dependent neuropathy.

It's really no big deal...you'll do fine. It's very accurate as they get to look directly at the small fibers, so they can determine density % as well as condition of the fibers.