I've really got to read more on this thread Mrs. D. I was reading one can OD on the B's and I may just be one. I take the Benfothiamine and the Jarrow B complex and then a spritz of B-12 a couple of times a day... but I must say that my PN is feeling better than in years. I really hope for some healing of the nerves in my lower legs and feet... course I don't let that stop me... I am a real work horse but am getting older and have to be more careful of my gallop. I was tested awhile ago...(years) May be a good time to do it again...Any personal experience of taking too much B's? Aloha.