BTW, here's a link to the full study ..
http://pubs.acs.org/doi/pdf/10.1021/nn506408v
It's staggering to see the number of researchers involved and the depth they released. Apparently the nanoballs used have been used to pass other chemicals into the brain before and they seem to totally dissolve and release dopamine gradually.
Best of all if this delivery system is already in use this could get released to phase 1 trials quickly.
The really nice part is that study was open source published and financed by the Indian government, not a drug company. It's bound to actually work then. IMO, this study has legs. We all may have to "vacation" in India someday to get on this protocol.
From the study ..
Conflict of Interest: The authors declare no competing
financial interest.
Acknowledgment. We are grateful to the Director of CSIRIITR,
Lucknow, India, for his continuous support in the present
work. K.C.G. thanks ICMR, New Delhi, India, for awarding a
Distinguished Scientist Chair. This work was supported by the
Department of Science and Technology as Woman Scientist and
Ramanna Fellow Grant to K.S. and CSIR network project
BSC0108 (MedChem) to R.K.C. Technical help of Mr. Punit Khare
flow cytometry analysis and Mr. Jai Shankar and Ms. Nidhi
Arjaria in TEM analysis is acknowledged. This is manuscript
communication number 3284.
Supporting Information Available: Nine supplementary figures.
This material is available free of charge via the Internet at
http://pubs.acs.org.