Animal studies are conducted to identify potentially helpful compounds that may later be shown to be both (a) safe and (b) effective in humans. It's the very, very beginning of building up the data needed to get us to, "Hey, this is a compound that works for these specific diseases."

Most compounds that show promise in rat studies never show the same positive effects (or effect sizes) in humans, or turn out to be unsafe at the dosing needed. That's just how it goes.

That's why I'm a little astounded when someone provides support for their claims relying on animal studies. That's not support, that's merely showing the compound is under study (like thousands of other compounds also under study). Such studies can say absolutely nothing about whether they'll help someone with "cognitive support" in humans.

DocJohn