I have found it to be helpful for NP although not a cure for PN.

There are several studies that back it but some drawbacks are not being able to legally travel with it and that inhaling it seems to be the most effective delivery method but that is not healthy for the lungs, and I believe the jury is still out on whether vaporizing is ok.

I use it in conjunction with a very small dose of hydro ER to manage my NP and for me, that seems to be effective for now.