My daughter has had regular cleanings w/out incident. Also had orthodontics and it did seem that she was unusually uncomfortable after tightenings, etc, but otherwise, it was uneventful for her. She recently had wisdom teeth out. We asked for general anesthesia and she took a narcotic pain killer for a day or 2 after. It was not fun, but I don't think wisdom teeth ever are! She does take 500mg Vitamin C daily as a cheap/safe insurance policy.