I wanted to report on my mom's experience with this, which unfortunately was not positive. It gave her very bad dyskinesias (worse than with Sinemet and Sinemet CR) and did not provide improved relief. It also made her sleep even worse.

We're disappointed this didn't work, and still looking for the next step, which I hope will be to try to significantly reduce Sinemet and try a different dopamine substance in its place. Sinemet gives her had side effects like debilitating shortness of breath. I am aware that reducing Sinemet can be dangerous and we would proceed with great caution.

I hope that those of you who have had a good initial experience with Rytary continue to experience improvement. It seems to be helping many people.