Argh. I looked up nortiptyline and is said something like an accidental overdose is easy to do. Yep, there's that liver warning for Cymbalta. Ghee this is tough b/c my doc will know I've done my homework. I've used bupropion for years, but it's lost it's effectiveness on me (10 years) and doesn't help with NP. 6 of 10 of my nerves in my lower legs are unresponsive-but I still walk (have a service dog for artificial lighting areas where I have most balance problems). Otherwise I hike, etc. I used to suffer from awful panic attacks in my 20's, so I have been to many, many years of counseling. I go weekly now. The docs thought I had borderline personality disorder for many years before the tumor was found! Lol - not.

I don't want liver problems (who does), but I want a life too. No one on this thread said anything too worriesome about Cymbalta (except the blowout) and I'm wondering if I can have my liver function tested regularly to be sure I'm not causing damage. Weight gain was listed on both; I lost 10 pounds when I quit Lyrica.

My NP is excruciating burning on the bottom of my feet, especially on the balls and for good measure stabbing pain occasionally, if I'm as active as a normal person (actually more active - I can't seem to stop if I get on a roll) or if I wear the same shoes all day (no high heels of course). I live in slippers at home. Sometimes the burning/stabbing is so bad, I cry. I have oxycodone I take regularly to prevent most breakthrough pain.

I really appreciate the responses and read each one with gratitude.

I'm glad I found you guys and hope to be of help to others as well.