Quote:
Originally Posted by glenntaj
--that benign fasciculation syndrome and small fiber neuropathy are quite the same thing, as small-fiber neuropathy refers specifically to dysfunction of small, unmyelinated and thinly myelinated sensory nerves and fasciculation involves muscle, and even the smallest muscles are ennervated by more thickly myelinated nerve fibers.
There's nothing that says, though, that a similar originating process or etiology may be behind both in some cases. Moreover, it is common to have mixed types of neuropathy, in which both myelinated and unmyelinated fibers are involved. Often, a process that attacks the axon--the nerve fiber itself, instead of the myelin covering--will affect both small and larger fibers. (Small-fiber syndromes, be definition, are axonal; larger fiber syndromes can be axonal, myelin-based, or both.)
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I suppose you are right. BFS is by definition a benign condition which involves the motor neurons but does not include any damage to them. The neurons are firing but it is unclear why. Maybe it would be more appropriate to just say that BFS can be a symptom of SFN - rather than to say they are the same thing.