Girija mentions tyrosine kinase inhibitors.

If we assume that:
- tyrosine kinase inhibitors are an effective treatment for PD.
- any commercial drugs will take at least five years to get to market and even then be too expensive for many.

Then it make sense to see if there are any natural substances with this property.

A quick Google gives:

- curcumin;

- genistein (found in broad (fava) beans, soybeans, coffee, kudzu).

Rick mentioned genistein back in 2012:
http://neurotalk.psychcentral.com/sh...ight=genistein

A quick sanity check:

- epidemiological results suggest that coffee consumption is negatively associated with PD.

- genistein crosses the BBB.

John