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Grand Magnate
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Join Date: Jan 2015
Location: Sydney, Australia.
Posts: 3,093
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Grand Magnate
Join Date: Jan 2015
Location: Sydney, Australia.
Posts: 3,093
|
Alpha-synuclein is a small protein (140 amino acid residues, about 14.5 kDa).
That means that it is too small to be seen directly by any current microscopy method.
It is possible to visualise the regions within a cell in which it is found using a specific antibody which has been tagged with a reporter enzyme or fluorescent probe.
However, this approach ("immunocytochemistry") just reports on regions (membrane-bound, in the nucleus, etc) rather than showing individual alpha-synuclein molecules.
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