A 20 year study on 82,802 women...

http://www.nejm.org/doi/full/10.1056/NEJMoa055317

A few snippets:

"A higher glycemic load was strongly associated with an increased risk of coronary heart disease..."

"We found that after taking into account confounding variables (especially smoking status), a low-carbohydrate diet was not associated with a risk of coronary heart disease in this large prospective cohort of women. In fact, when vegetable sources of fat and protein were chosen, the low-carbohydrate-diet score was associated with a moderately lower risk of coronary heart disease than when animal sources were chosen."