Quote:
Originally Posted by zanpar321
The past 5 years since I was diagnosed with PD, I've read thousands of articles and studies postulating the possible causes of PD. Lately though I wonder if PD may be caused by a lack of oxygen to neurons in the brain. Sure a number of things such as toxins, physical damage (e.g. boxing, car accident etc.) may have occurred, I believe they have all somehow impaired the flow of oxygen. Lately, I've discovered that clumps of excess alpha synuclein apparently impairs/affects the activity of red blood cells which bring oxygen into the brain. Also, dozens of studies clearly show that PWP who exercise vigorously and regularly (which improves oxygen intake) seem to do much better. I could be wrong, but I believe that improving oxygen flow is crucial to stopping/reversing PD.
http://www.naturalnews.com/038930_sl...lzheimers.html |
1. i've read that if we lived longer we'd all get pd since we lose a certain number of dopamine producing cells every year naturally as we age.
2. assuming that we all have a surplus of dopamine producing cells and we have to lose at least 80% of them before pd symptoms occur - i've read this % might be lower than 80%, and since there is no definitive biomarker tests to detect the start of pd before it can be visually detected, there's no way to tell when your abnormally large loss of neurons started. could have been in the womb - you could have been born with fewer dopamine producing neurons!! could have been a concussions from sports or an accident, exposures to a toxin, a fever, a systemic prescription drug, something that happened years ago but your pd didn't manifest itself until normal loss of neurons finally resulted in your displaying pd.
3. lots of research is being done looking for biomarkers in young people not showing pd to try to get closer to the time neurons started to be lost and closer to the cause.
4. people who exercise might have a lower incidence of pd and alzheimers but the incidence is pretty low to begin with. a lot of obese, out of shape people, people with coronary disease, arteriosclerosis, strokes, don't get pd. if they did get pd more often than be accounted for by chance, it would have been detected when analyzing data in countries like sweden which have extensive national medical records.
5. smokers have a lower incidence of pd, i assume they have less O2 flow to the brain at times since nicotine is a vasoconstricter.
6. people with pd who travel to high altitudes don't report their pd gets worse, there are anecdotal reports that they feel better.
7. i agree 100% exercise is good for you mentally and physically, a ton of research on that.
http://neurotalk.psychcentral.com/ar.../t-140074.html