Quote:
Originally Posted by mrsD
Yes, I do think this is really important. When we first started here on NT... the DNA testing was not really easily available.
But I have watched over the years, and all the posts, where people gravitate here because all other venues have failed in some way.
Now after 2 years we've had some posters do the 23andme testing and all of them come back with mutations. The old % suggested by Merck when the research first came out was 10% have this. Then a doctor came on our General board and stated that he specializes in this, and went to a new seminar and they were raising the % to 30 (and perhaps even more).... so it does seem that methylation errors are becoming very significant.
The testing will also show COMT errors...which are also important.
If a person has only one chromosome affected, they limp along until they reach a state where they cannot function anymore.
The patients who have the double mutation (homozygous), are affected at earlier ages, it seems.
So yes, I think getting the testing may be helpful for you.
|
Well, I purchased the 23 and Me testing, and the kit arrived Friday. I'll see what the results are in several weeks.
BTW, I have a sister who had the 23 and Me testing done a while back, primarily for ancestry purposes. After talking about this with her, she ran her results through Genetic Genie - and she found that she is heterozygous for the MTFHR 1298 gene, and several of the COMT genes - but normal for the MTFHR 677 gene. It will be interesting to see what my results say.