Thanks, both of you. The last time I took methimazole, I took it for less than three months, and got six years of total remission out of it. If you use thyroid suppressants for long enough, they can send you into permanent remission. I think there's a good chance I'm two months' worth of methimazole away from cured--my endo had hoped that my previous flare would be my last.

That's one reason I don't want to do the RAI if I don't have to. Another is that I'm not confident I'll ever be happy with how I feel on synthroid. And even if I eventually get it right, I'm terrified of the months of being hypo. I have a ton of people depending on me. I can't afford to check out even temporarily--I'm afraid of the fatigue, and terrified of the possibility of depression. I think I would never recover from that no matter what my numbers said.

Here are the links I found about the methimazole-MG connection. They're just case reports, but one of the articles suggests a mechanism by which methimazole may have an immuno-modulatory effect. Because I got MG after taking methimazole, I'm especially wary.

http://www.ncbi.nlm.nih.gov/pubmed/20635587
http://www.ncbi.nlm.nih.gov/pubmed/22957965
http://www.ncbi.nlm.nih.gov/pubmed/1798220

Here's a case report of methimazole causing more autoimmune problems in someone who has Graves and MG:

http://www.jscimedcentral.com/Geront...ogy-2-1021.pdf