Many thanks to everyone who replied. Susanne it does make sense that this has been quitely bubbling away until the meds could prevent no more Definitely in the last three months his bad days were outweighing his good ones. I just never thought about it until you put it in perspective.

Mrs. D - yes he was a truck mechanic all his life so exposed to solvents, waste oil etc. Before the days when they wore gloves! We were also born and lived in an area in England where they tested atomic weapons - although we were constantly assured there had been no radiation leaks I have my doubts

Do we just ask for heavy metal testing to be done? Is it a common test? Even if it comes back postive would it help though? Surely the damage is done?

He has had the oral 2 hour glucose test periodically over the years and his range is always normal. Other tests: C3, ESR, Anti DNA and ENA. Also tested for MS.

What else should be looked at?

I assumed this is also affecting his automatic nerves just by what I've read, although no one has suggested this.

Linda