I have not read the Grain Brain by Dr. Perlmutter, but I often hear him on my NPR radio and PBS TV....talks about so many alz patients have low cholesterol. Our brains need good fats and sadly too many folks are in fear of the cholesterol. So end up on statins or cut out fats... My folks ate fats and traditional foods and lived into 90's...I never heard the word cholesterol back in their days. They were still sharp minded when they left.