Yes, the pens are more convenient to carry and do not need refrigeration after they have been placed in use.

I find it a little more comfortable to inject room temperature insulin than the cold refrigerated insulin.

The temperature of the insulin may also have a slight effect upon the speed of action within the body just as the injection site may also have a slight effect upon the speed of action within the body.

I don't think either of these are very significant, temperature or injection site location, but it has been stated that there may be a slight delay in action.