half go at my Duke Neuro's instruction. Did 20 mg for two weeks and then was supposed to do 10 mg for 6 more. Saw no improvement after 2 weeks and thought I might be having some side effects (which turns out I don't think the prednisone was causing), so I weaned off.

Now he wants me to do a 2 week at 40 mg trial and then 6 weeks at 20 mg. He said a combo of the higher dose along with the fact that I was only on the first trial for two weeks may make a difference this time

I'm pretty convinced that my SFN is autoimmune based considering my ANA is consistently at least moderate positive and last time it was checked was the highest positive on Duke's ranges. That, along with the fact that I have psoriasis, there's something abnormal about my capillary beds under my fingernails, and because I have had small pleural and pericardial effusions in this past. I think all of these pretty strongly point to an autoimmune process as my culprit, and I think the neurologist thinks it's highly likely as well but still, I believe, he keeps the official diagnosis as "idiopathic'

I guess I'm skeptical of the prednisone and don't like the idea of taking it. Then, when I read a lot of good things about IVIG for small fiber neuropathy I get frustrated.

Just wish the IVIG was an available option at this point. But I guess I might just do the prednisone trial and then, if it does not help, insist I want to pursue IVIG and see what happens.

I see him next week so we'll see what comes out of it.