Do you know your lab reading: the range in my area is 211-400. My B12 has been coming in high as I've been taking B12 Methyl for many years. I still take 2000mcg Now Foods Methylcob just about every day. My doc has no issues with my B12 being high and the lab reports it Optimal. Some folks I know take 5000mcg and I think too many take 1000mcg daily which I believe is too little. Why not work with the 2000mcg tabs for a while. Or go with the 5000mcg...again do you know where your readings are? I think most are deficient anyway. My B-12 are lozenges dissolve in my mouth. C