I have nerve damage from hip replacement and tried to work with LDN prior to 2010 as I wanted to try everything to NOT do this surgery, but I could not get LDN work for me, I tried for 6 months with prompting from the LDN group and for me it was more trouble than worth it...I never got beyond .5mg but I know it helps MS patients and others. I have a friend who deals with CFS and she is talking about trying LDN, her sister RA is trying it now.

Hard to know until one trys, I had 1 terrific day on the .5mg and nothing after that...horrible constipation that I had to battle to continue to work with LDN.