i would call and ask the neuro for a 25/100 sinemet rx right now, with directions like "take one tablet by mouth up to 3 times a day" so your husband can have some extra sinemet to try before the visit, this seems like an emergency to me. you can refill it as needed if there is an insurance/cost issue. and maybe increase the qty on the CR rx. you can split the 50/200CR tablets and take 1/2 tablet or 1.5 tablets, i've found taking 2 too much for me and sometimes it kicks in much later than expected and i've taken a 25/100 thinking the 50/200 isn't going to work and then it kicks in, get quite nauseaus.

constipation definately decreases the affect of sinemet and you need to drink a large glass of water with each dose.