Toe curls are serious because they make balance much worse and can lead to pressure ulcers on the ball of the foot. My husband's neuro has given him Botox injections, which have relaxed the toes. On the right foot, his great toe curled upward and the second toe curled under. However on the left foor the woes are all curling under. The Botox has made a great difference in his legs feeling more relaxed, better balance for the few transfer steps he can take, and all the ulcers have healed. Is this a treatment option for you?