Still trying to understand what they're saying, but it's difficult because when I read the scientific research reports I only understand about every fourth word.
If I try to get this is in plain English, this is what I'm gathering...
- ER Stress plays a significant role in neuropathic pain.
- ER Stress is mitigated by EPA and DHA which have an analgesic effect in the body.
- EPA and DHA are broken down by soluble epoxide hydrolas (sEH) into diols taking away their analgesic effects.
- The idea is to block sEH from breaking down EPA and DHA so they can in turn block ER Stress.
This is the UC Davis patent for "Treating Neuropathic Pain with sEH Inhibitors." Let the games begin.
http://www.google.com/patents/US20150065540
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