Hi Flame. I feel for you.

BTW, it was a doctor who responded. He's truly the best guy imaginable. He's written a great book about RLS with two other doctors and works an unbelievable amount on that website answering emails.

Reducing the Effexor - or changing it to something more RLS friendly, like Wellburtrin - could completely reduce the need for the Mirapex since it seems it started when the ADs started. They are notorious for causing RLS in people who never had it before. As Dr B said to you, Mirapex can (and often is) prescribed in low doses. When I was on it, I started at .125 mg. I had other problems with it and ended up at .75 mg before I stopped it completely. Your husband may need the higher dose to control the RLS because of the AD. With a different AD or a lower dose of it, he'd probably need less Mirapex.