I believe the relief does hang over all the way into the next afternoon. But every time I go on this drug I want off of it . If I do go off of it I find myself having to return to it because of the pain level.

I would say if you can avoid taking it to do so. It's a masking drug. It isn't a cure. It attempts to trick the brain to not see the pain signals that are being sent from the nerves. But there are clear side effects and I really think it's a survival issue. For some they have no choice but to take it. It's not something I think anyone should be on long term. I found Lyrica got rid of a lot of the pain but it was an awful drug to take, total zombie time, walking around like Frankenstein and cymbalta made me literally want to end my life.