For those of us who have adrenal failure/insufficiency, taking hydrocortisone is actually replacing what our bodies should be producing but aren't. This puts us in the same category as people who have normal adrenal function, and therefore shouldn't cause any suppression of antibody production. I agree that taking corticosteroids on top of normal adrenal function, in high doses, will suppress antibody production--this is why they use it, after all. It also suppresses the adrenal glands, which is why you have to taper off slowly.

But if your adrenal glands don't produce enough to begin with, your life literally depends on taking replacement cortisol. Read about Addison's crisis--this is not where we want to go. I would strongly encourage you to keep taking the hydrocortisone, and find an endocrinologist who can evaluate you for Schmidt's syndrome: adrenal failure/insufficiency plus either/both of thyroid failure/insufficiency and/or Type ONE diabetes.

As Laurie said, there is a very short effect from hydrocortisone--it is not like prednisone. Cortisol is necessary for normal cell function in your body. Adrenal failure/insufficiency is not a condition to take lightly--you can die from it.

Please be careful ... just sayin'.