I reduced my requip from 18 mgs down to 6 mgs. But I did it over two years, very slowly. I was told not to do it but I knew I had reached my limit. I had become very restless and agitated. Sort of like a caged animal. I had the urge to bolt, I would find myself out driving around in my car not sure of where I was going. I believe you can reduce any medication but it has to be done very slowly.