I often hear people reporting positive effects in mood and energy with SAM-e.
Here is an article which gives some information on SAM-e studies, lists a book written by SAM-e investigators and also lists references:
http://www.psychiatrictimes.com/depr...m-e-depression
WebMD lists some uses, interactions, contraindications, etc.:
http://www.webmd.com/vitamins-supple...dientname=same
As always, please be careful. Study up. Talk with your physician.

DejaVu