John

Can I ask you for your thoughts on point 13. Rapid gastric emptying is understandable. But what is the likely inhibiting process with constipation ? Is it fecal matter physically blocking absorption, a slowing of the digestive process that prevents the meds getting to the right part of the gut or something else.
How much do we estimate this would alter drug levels and would this be primarily a constant release specific problem ?

I guess this is why exercise,diet,fluid intake is so important .




Nigel